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Redd1 antibody

WebNov 20, 2024 · REDD1 protein was upregulated in the activated primary hepatic stellate cells and transforming growth factor-β (TGF-β)-treated LX-2 cells. REDD1 mRNA levels were also elevated by TGF-β treatment. TGF-β signaling is primarily transduced via the activation of the Smad transcription factor. WebBethyl Laboratories Anti-REDD1 Polyclonal, Catalog # IHC-00542-T. Tested in Immunocytochemistry (ICC/IF) applications. This antibody reacts with Human samples. Supplied as 10 µL purified antibody (0.25 mg/mL).

Mouse anti-REDD1 Monoclonal Antibody [1G11] - Fortis Life

WebREDD1 is a reported alias name for the human gene DDIT4, or 'DNA damage inducible transcript 4'. The 232-amino acid protein is a member of the DDIT4 family. The cellular localization is predicted to be cytoplasmic and mitochondrial. See the supplier page to learn important antibody details, such as target specificity and designated applications. WebJul 12, 2024 · ATF4-induced REDD1 and Sestrin2 expression in response to metformin plays an important role in mTORC1 inhibition independent of AMPK activation, and this signalling pathway could have therapeutic value. ... membranes followed by immunoblotting with the specified primary and horseradish peroxidase-conjugated secondary antibodies. The … fifo autodiely https://connersmachinery.com

Rabbit anti-REDD1 Antibody - Fortis Life Sciences

WebREDD1 pT23/25 Antibody is ideal for researchers interested in cancer research. Application Note Anti-Phospho-Thr23/25 REDD1 Antibody is tested for Western Blots and is specific … WebJun 26, 2009 · REDD1 (regulated in development and DNA damage responses 1), a hypoxia-inducible factor-1 target gene, has a crucial role in inhibiting mammalian target of rapamycin complex 1 (mTORC1) signalling during hypoxic stress. However, little is known about the signalling pathways and post-translational modifications that regulate REDD1 function. WebJun 26, 2009 · REDD1 (regulated in development and DNA damage responses 1)is a recently described component of the stress response. REDD1 was first identified as a gene … grilled chicken and penne pasta

Anti-REDD-1/DDIT4 antibody (ab106356) Abcam

Category:REDD-1 Antibody (A-4) SCBT - Santa Cruz Biotechnology

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Redd1 antibody

siRNA Knockdown of REDD1 Facilitates Aspirin-Mediated …

WebMar 1, 2016 · REDD1 is a transcriptional target gene of p53 and HIF-1, and an inhibitor of mTOR (mechanistic target of rapamycin) complex 1 (mTORC1)-signaling through PP2A-dependent interaction, making it an important convergence point of both tumor suppression and cell growth pathways. WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here. Our RabMAb ® technology is a patented hybridoma-based technology ...

Redd1 antibody

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WebREDD1 (regulated in development and DNA damage response 1) is a direct transcriptional target of HIF. It plays a role in the TSC/mTOR pathway as a regulator upstream of the TSC1/2 complex. In response to both hypoxia and energy stress, REDD1 inhibits mTOR activity in a TSC-dependent manner. WebThe antibody performs great on human cell extract, as evidenced by a single immunoreactive band. The antibody performs moderately well on mouse skeletal muscle …

WebAug 24, 2015 · REDD1 is a highly conserved stress response protein that is upregulated following many types of cellular stress, including hypoxia, DNA damage, energy stress, ER … WebJun 9, 2016 · REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-κB activation. View PDF. In Nature Communications on 22 October 2024 by Lee, D. K., Kim, T., et al..

WebREDD1 Antibody (A302-169A) in ICC/IF. Detection of human REDD1 by immunocytochemistry. Sample: NBF-fixed asynchronous, Cobalt-treated HeLa cells. … WebMar 1, 2016 · REDD1 is a transcriptional target gene of p53 and HIF-1, and an inhibitor of mTOR (mechanistic target of rapamycin) complex 1 (mTORC1)-signaling through PP2A …

WebApr 28, 2015 · In Redd1−/− mice, deregulated ATG4B activity and disabled autophagic flux cause accumulation of defective mitochondria, leading to impaired oxidative …

WebOct 13, 2024 · Regulated in development and DNA damage response (REDD)1 is a conserved and ubiquitous protein, which is transiently induced in response to multiple stimuli. Acting … fifo asynchronousWebREDD1 (1) REDD1 specific (1) Tested Applications WB (2) ELISA (2) FC (1) IHC (1) chIP (1) CoIP (1) IP (1) IF (1) More KD/KO Validated KD/KO (1) Species Reactivity Human (2) Gerbil (1) Mouse (1) Pig (1) Rabbit (1) Rat (1) Squirrel (1) More Conjugation Unconjugated (2) Clonality Monoclonal (1) Polyclonal (1) 2 product results for: "REDD1" grilled chicken and peachesWebsiRNA Knockdown of REDD1 Facilitates Aspirin-Mediated Dephosphorylation of mTORC1 Target 4E-BP1 in MDA-MB-468 Human Breast Cancer Cell Line ... (for probing p-4E-BP1, 4E-BP1, and REDD1) or AP-conjugated secondary antibodies (for β-actin). The blots were washed again with TBST three times and the proteins were detected using Super Signal … grilled chicken and rice west lafayette