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Hpebp4

WebExpression of hPEBP4 was correlated with tumor regression in the resected specimen and the clinical outcome of the patients as well. Results: We found that high expression of hPEBP4 was associated with radioresistance in both univariate and multivariate analyses, and patients with a high hPEBP4 expression had a poorer progression-free survival than … Webapoptotic molecule. Once hPEBP4 is silenced, the breast cancer cells became more sensitive to TNF·-induced cellular apoptosis, indicating that the hPEBP4 may be a candidate target for breast cancer therapeutics (15,16). On the basis of previous studies of hPEBP4, we aimed to identify the mouse homolog of hPEBP4 (mouse PEBP4, mPEBP4) and

PEBP4 protein expression summary - The Human Protein Atlas

WebFig. 2 Expression pattern of hPEBP4. RT-PCR analysis of hPEBP4 mRNA expression in human hematological tumor cells (A), freshly isolated human cells (B), and solid tumor … WebhPEBP4 RNA Interference Assay—For stable silencing of hPEBP4 expression in human prostate cancer LNCaP cells, the cells were transfected with the hPEBP4-RNAi or Neo plasmid using Lipofectamine reagent as described previously (19). 48 h after transfection, the cells were screened under 0.6 mg/ml G418 mineral county school district superintendent https://connersmachinery.com

Promotion of cellular migration and apoptosis resistance by a …

Web15 ott 2005 · Results: hPEBP4 was found to be expressed in up to 50% of breast cancers but in only <4% of normal breast tissues. Silencing of hPEBP4 potentiated tumor … Web25 feb 2013 · Rituximab is the first line drug to treat non Hodgkin’s lymphoma (B-NHL) alone or in combination with chemotherapy. However, 30–40% of B-NHL patients are unresponsive to rituximab or resistant after therapy. Human phosphatidylethanolamine-binding protein 4 (hPEBP4) is a novel member of PEBP family and functions as an anti … Web16 apr 2010 · hPEBP4 (human phosphatidylethanolamine-binding protein 4) has been identified to be able to potentiate the resistance of breast, prostate, and ovarian cancers, … mineral county real estate taxes

hPEBP4 Resists TRAIL-induced Apoptosis of Human

Category:A modified HLA-A*0201-restricted CTL epitope from human …

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Hpebp4

Human Phosphatidylethanolamine-Binding Protein 4 Promoted …

Web25 nov 2013 · hPEBP4 functions as an anti-apoptotic molecule, and its expression is positively correlated with the severity of prostate and breast cancer. 6, 7, 8 In this study, … Web16 feb 2007 · hPEBP4 promotes AKT activation and inhibits ERK activation in human prostate cancer cells. A, DU145 cells were stably transfected with hPEBP-B, p75PEBP4 …

Hpebp4

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Web29 gen 2024 · Abstract. We previously identified human phosphatidylethanolamine-binding protein 4 (hPEBP4) as an antiapoptotic protein with increased expression levels in … Web1 set 2006 · Therefore, silencing of hPEBP4 in CaoV-3 ovarian cancer promotes TRAIL-induced apoptosis, and the increased MAPK activation is required for the apoptosis sensitization. All these data indicate that silencing of hPEBP4, an important potential target, may be a promising approach for the treatment of ovarian cancer.

WebThe RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell … Web25 set 2024 · Withdrawal: hPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways.

Web16 lug 2010 · ERα-mediated transcriptional activation is the most important mechanism by which estrogen exerts its carcinogenic effect ().To investigate the hPEBP4 effect on ERα signaling, we examined ERα-mediated transactivation through ERE in the hPEBP4-silenced MCF-7 cells, which were transfected with the vectors containing a luciferase reporter … Web1 feb 2007 · Anti-apoptotic hPEBP4 silencing promotes TRAIL-induced apoptosis of human ovarian cancer cells by activating ERK and JNK pathways. 13: 25038915: 2014: Downregulation of PEBP4, a target of miR-34a, sensitizes drug-resistant lung cancer cells. 13: 19197339: 2009: Regulation of human myoblast differentiation by PEBP4. 10: …

WebHuman phosphatidylethanolamine-binding protein 4 (hPEBP4) is recently identified by us as an anti-apoptotic molecule and a potential candidate target for breast cancer treatment. …

Web25 nov 2013 · Increased hPEBP4 expression in the metastatic breast cancer and lymph node metastases. To address the relationship between hPEBP4 expression and the metastasis of breast cancer, human tissue ... moscow mall hoursWebTips for better search results. Ensure correct spelling and spacing - Examples: "paper jam" Use product model name: - Examples: laserjet pro p1102, DeskJet 2130 For HP … moscow lvpWeb16 feb 2007 · hPEBP4 Promotes Akt Activation and Inhibits ERK Activation in Human Prostate Cancer Cells−It is demonstrated that Akt and ERK pathways are important in regulating survival of prostate cancer cells, and increased Akt activation and ERK deactivation strongly predict poor clinical outcome in prostate cancer ().Because … moscow mailbagWebDownload scientific diagram Silencing of hPEBP4 increases ER degradation to repress ER expression. A and B, MCF-7 cells were transfected with hPEBP4-specific siRNA (hPEBP4 siRNA) or mutated ... moscow mall on firemoscow management bostonWebDownload the latest drivers, firmware, and software for your HP EliteBook 8440p Notebook PC.This is HP’s official website that will help automatically detect and download the … moscow louisianaWeb23 ago 2016 · Human phosphatidylethanolamine-binding protein 4 (hPEBP4) is a well-established antiapoptosis molecule in recent years. It has also been demonstrated to be involved in the radioresistance of rectal cancer. The objective of this study was to determine whether IOI-42, a chemical inhibitor of hPEBP4, could sensitize rectal cancer cells. moscow maine weather for a week