WebAbstact. Fibulin-2, an extracellular matrix protein expressed by normal epithelia, was found to be down-regulated in several breast cancer cell lines. Fibulin-2 protein expression was also decreased in breast cancer tissue samples as evaluated by immunohistochemistry. Reintroduction of Fibulin-2 into breast cancer cell lines that do not express ... WebFibulin-5/DANCEは448アミノ酸から成る分子量66kDaの分泌性タンパク質で、N末領域にRGD (arginine-glycine-asparticacid) 配列を有し、α5β1, αvβ3, および αvβ5インテグリン …
A High-Throughput Cell-Based Gaussia Luciferase Reporter Assay …
WebApr 11, 2024 · IntroductionEarly-stage accurate diagnosis of malignant pleural mesothelioma (MPM) has always been a formidable challenge. DNA and protein as biomarkers for the diagnosis of MPM have received considerable attention, and yet the outcomes are inconsistent.MethodsIn this study, a systematic search employing … WebCloning. Humanized Gaussia luciferase (GLuc) was mutated (M43I and M110I) to yield a luciferase enzyme with glow-like properties (eGLuc2) and thus more suitable for HTS. 16,17 Genes encoding for eGLuc2, fibulin-3 fused to a C-terminal eGLuc2, or untagged fibulin-3 or fibulin-5 were generated in the pENTR1A Dual Selection entry plasmid (Life … jesus alvarez landscaping
Cells Free Full-Text Transcriptome Analysis of Hypoxic Lymphatic ...
WebMar 21, 2024 · FBLN5 (Fibulin 5) is a Protein Coding gene. Diseases associated with FBLN5 include Macular Degeneration, Age-Related, 3 and Cutis Laxa, Autosomal … WebDescription. An autosomal dominant demyelinating form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and … WebApr 14, 2024 · The complement system is crucial for immune surveillance, providing the body’s first line of defence against pathogens. However, an imbalance in its regulators can lead to inappropriate overactivation, resulting in diseases such as age-related macular degeneration (AMD), a leading cause of irreversible blindness globally affecting … lampen jaren 20-30