WebOct 1, 1996 · In addition to this enzyme, cyanobacteria also possess a unique enzyme, fructose-1,6-/sedoheptulose-1,7-bisphosphatase (FBP/SBPase), that can hydrolyze both FBP and SBP (Tamoi et al., 1996). A similar enzyme that hydrolyzes both FBP and SBP has been isolated from spinach leaves (Gontero et al., 1984a,b). Show abstract WebWe describe the crystal structure of cy‐FBP/SBPase +AMP+FBP, which is dynamic and harbors at least three regulatory domains. The state of cy‐FBP/SBPase is changed among three potential states in the presence of different regulators: initial non‐active dimer state, non‐active tetramer state and active tetramer state. In the non‐active dimer state, a …
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WebIn the present study, we targeted the substrate binding pocket of cy-FBP/SBPase. A series of novel hit compounds from the SPECs database were selected by using a pharmacophore-based virtual screening strategy. Most of the compounds tested exhibited moderate inhibitory activities (IC50 = 20.7-176.9 μM) against cy-FBP/SBPase. WebApr 1, 2012 · Fructose-1,6-/sedoheptulose-1,7-bisphosphatase (FBP/SBPase) is a potential important target enzyme for finding inhibitors to solve harmful algal bloom. In this paper, … dhl paketsuche international
Overexpression of a cyanobacterial fructose-1,6 …
WebJul 22, 2024 · FBAase and SBPase are two key enzymes in regeneration of RuBP. FBAase catalyzes two reactions: one is the conversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP) … WebJun 1, 2013 · In this study, as potential inhibitors of Cy-FBP/SBPase, a series of novel chromone-connecting benzohydrazone compounds (Novel N′-((4-oxo-4H-chromen-3 … WebWe identified a series of residues important for FBP and AMP binding, and suggest formation of a disulfide linkage between Cys75 and Cys99. Further analysis indicates … dhl paketversand international preise