WebHIF1A. Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the HIF1A gene. [5] [6] [7] The Nobel Prize in … WebMar 29, 2024 · Identification of circWSB1 in BC cells in response to hypoxia. a Western blot analysis of HIF1α in MCF-7 cells cultured under normoxia or hypoxia for 48 h.b Volcano …
Hypoxia-induced circWSB1 promotes breast cancer progression …
WebHypoxia-inducible factor-1 (HIF-1) has been recognized as an important cancer drug target. Many recent studies have provided convincing evidences of strong correlation between … WebApr 16, 2024 · HIF1α is a transcription factor that regulates the expression of glycolytic-related genes. 18 SIRT3 also inhibits tumor progression by targeting the manganese superoxide dismutase (MnSOD), reducing the production of reactive oxygen species (ROS) and genomic instability. 19 Therefore, the stability of HIF1α is regulated through SIRT3 … importance of eustress
Histone methyltransferase SETD1A interacts with HIF1α to …
WebOverexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors. A higher level expression seen in pituitary tumors as compared to the pituitary gland. 1 publication. WebPubMed WebMar 21, 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, Multiple, Ollier Type.Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated degradation.Gene Ontology (GO) … importance of evaluation and control