WebJan 29, 2024 · Aklief is the first topical, prescription-strength retinoid proven to be effective for this purpose. “The low concentration correlates with lower systemic absorption so that … WebMar 30, 2024 · Differin (adapalene) is another retinoid and is mainly used to treat acne. It’s now available over-the-counter, meaning without a doctor’s prescription. While there isn’t as much research on Differin, some studies show that it can improve signs of sun damage.
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