Arf gap domain

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August undefined, 2024

Web19 feb 2024 · AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is a protein that belongs to the Arf GAP (GTPase activating protein) protein family. These proteins act as GTPase switches for Arfs, which are Ras superfamily members, being therefore involved in signaling … Web1 gen 2002 · ARAP1 is the first PH domain-containing Arf GAP found to associate with the Golgi apparatus. Overexpression of another Golgi-associated Arf GAP, Arf GAP1, causes loss of the Golgi apparatus and mixing of Golgi and endoplasmic reticulum proteins Aoe et al. 1997, Cukierman et al. 1995.

GTPase-activating Protein - an overview ScienceDirect Topics

Web24 mar 2009 · pthr45899:sf3 arf-gap with rho-gap domain, ank repeat and ph domain-containing protein 1 1 hit; pthr45899 rho gtpase activating protein at 15b, isoform c 1 hit; … Web11 apr 2024 · The amino acid sequence shows similarity with arf-GAP GTPase domain on performing a protein blast. (B) The orfs from the partner genes in the fusion transcript HOXD11 and AGAP3 along with their protein domains. drugsource medicaid

(PDF) The GAP Domain and the SNARE, Coatomer and Cargo …

Web7 nov 2024 · This observation prompted us to analyze whether the Arf-GAP domain of GTS1 could also complement the growth defect of a gts1 strain. We transformed plasmids bearing either the full length GTS1 under control of its own promoter, the 5’-end of GTS1 bearing the Arf-GAP domain or the 3’-end of GTS1 with the UBA-Pro-Gln domains both … Web1 giu 2007 · In contrast, GAP IP4BP is constitutively membrane bound but requires binding of inositol 1,3,4,5 tetraphosphate, the PLC-mediated cleavage product of PIP3 to its PH domain for GAP activity (Cullen and Lockyer, 2002). β2-chimaerin, a GAP for Rac, contains an SH2 domain, a C1 domain responsible for DAG binding, and a RhoGAP domain. http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00105 combining hike

Arf GAPs and Their Interacting Proteins - Wiley Online Library

Arf gap domain

Web5 ago 2016 · ARAP3 (Arf-GAP with Rho-GAP domain, ANK repeat, and PH domain-containing protein 3) is unique for its dual specificity GAPs (GTPase-activating protein) activity for Arf6 (ADP-ribosylation factor 6) and RhoA (Ras homolog gene family member A) regulated by phosphatidylinositol 3,4,5-trisphosphate and a small GTPase Rap1-GTP … WebNational Center for Biotechnology Information

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WebThe National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C. Web21 apr 2024 · a common Arf GAP domain necessary for catalyzing. the hydrolysis of GTP bound to Arf. 2, 4-6. The Arf. GAPs outn umber the Ar fs, with 31 h uman gene s. encoding Arf GAPs, some of which encode ...

Web5 nov 1999 · The crystal structure of the PAPbeta ARF-GAP domain and the C-terminal ankyrin repeats has been determined at 2.1 A resolution. The ARF-GAP domain … Web13 apr 2010 · Gcs1p together with another Arf GAP, Glo3p, is essential for retrograde transport from the Golgi to the ER, demonstrating its importance in the regulation of Arf …

Web10 dic 2010 · AGAP1 (Arf GAP, GTPase, ankyrin repeat, PH) (also known as Centaurin-γ2) is an 89-kDa protein in both mouse and human cells that is expressed ubiquitously. It is a multi-domain protein comprised ... Web21 mar 2024 · ASAP2 (ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 2) is a Protein Coding gene. Diseases associated with ASAP2 include Bulbar Polio and Multiple Epiphyseal Dysplasia Due To Collagen 9 Anomaly.Among its related pathways are Arf6 trafficking events and Vitamin D receptor pathway.Gene Ontology (GO) annotations …

Web12 apr 2024 · Auxin response factor (ARF) is an important transcription factor that regulates the expression of auxin-responsive genes by direct binding to their promoters, which play a central role in plant growth, development, and response to abiotic stresses. The availability of the entire Coix (Coix lacryma-jobi L.) genome sequence provides an opportunity to …

Web18 mag 2011 · All ARF GAPs contain the conserved zinc-finger ARF GAP catalytic domain in addition to other domains responsible for membrane recruitment, regulation of GAP activity and other scaffolding functions... combining households with parentsWeb11 dic 2024 · Contacts between WDR41 and the DENN domain of SMCR8 drive the lysosomal localization of the complex in conditions of amino acid starvation. The structure suggested that C9ORF72-SMCR8 is a GTPase-activating protein (GAP), and Su et al. (2024) found that C9ORF72-SMCR8-WDR41 acts as a GAP for the ARF family of small … combining hookWebArf GTPase-activating proteins (Arf GAPs) were first identified as regulators of the small GTP-binding proteins ADP-ribosylation factors (Arfs). The Arf GAPs are a large family of proteins in metazoans, outnumbering the Arfs that they regulate. The members of the Arf GAP family have complex domain s … combining households